Tazarotenic acid
SIGMA/SML1619 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 118292-41-4
Empirical Formula (Hill Notation): C19H17NO2S
Molecular Weight: 323.41
MDL Number: MFCD00872121
Linear Formula: C19H17NO2S
Product Type: Chemical
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1619-25MG.
This image depicts SML1619-25MG.
| assay | ≥98% (HPLC) |
| color | white to light brown |
| form | powder |
| InChI | 1S/C19H17NO2S/c1-19(2)9-1 |
| InChI key | IQIBKLWBVJPOQO-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CC1(C)CCSC2=C1C=C(C#CC3=C |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Tazarotene is transformed to tazarotenic acid with the help of esterases. Tazarotenic acid regulates the pathogenic aspects of psoriasis through normalizing abnormal keratinocyte differentiation. It possesses strong anti-hyperproliferative effects in skin and reduces inflammation. |
| Biochem/physiol Actions: | Tazarotenic acid, an active metabolite of tazarotene, is a potent and selective agonist of the retinoid receptor (RAR) that binds to RARα, RARβ, and RARγ. Tazarotenic acid relatively selective activates RARβ and RARγ. Tazarotenic acid is a first xenobiotic substrate of human retinoic acid hydroxylase CYP26A1 and CYP26B1. |
| Biochem/physiol Actions: | Tazarotenic acid, an active metabolite of tazarotene, is a potent and selective agonist of the retinoid receptor (RAR). |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352106 |