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MSP-3

SIGMA/SML1623 - ≥98% (HPLC)

Synonym: N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide

CAS Number: 1820968-63-5
Empirical Formula (Hill Notation): C16H19NO3S
Molecular Weight: 305.39
Linear Formula: C16H19NO3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1623-5MG 5 mg
 $119.00
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assay ≥98% (HPLC)
color white to beige
form oil
InChI 1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
InChI key HCUVEUVIUAJXRB-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
storage temp. room temp
Biochem/physiol Actions: MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.
Biochem/physiol Actions: TRPV1 agonist protective against oxidative stress
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319
Precautionary statements P305 + P351 + P338
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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