TFCA
SIGMA/SML1626 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 895700-18-2
Empirical Formula (Hill Notation): C18H16F3NO3
Molecular Weight: 351.32
Linear Formula: C18H16F3NO3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C18H16F3NO3/c1-24-15-9 |
InChI key | KFWWXJZNIMFFRO-ONNFQVAWSA |
Quality Level | 100 ![]() |
SMILES string | O=C(NC1=CC=C(C(F)(F)F)C=C |
solubility | DMSO: 25 mg/mL, clear |
storage temp. | room temp |
Biochem/physiol Actions: | TFCA is a Liver X receptor α (LXRα) antagonist that reduces lipid accumulation and fatty liver in mice. Apparently TFCA binds to the LXR? ligand binding domain and induces interaction with NCoR corepressor. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | room temp |
UNSPSC | 12352200 |