Brassinin
SIGMA/SML1635 - ≥98% (HPLC)
Synonym: Brassinine; Methyl N-
CAS Number: 105748-59-2
Empirical Formula (Hill Notation): C11H12N2S2
Molecular Weight: 236.36
MDL Number: MFCD01632490
Linear Formula: C11H12N2S2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C11H12N2S2/c1-15-11(14 |
InChI key | QYKQWFZDEDFELK-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | S=C(SC)NCC1=CNC2=C1C=CC=C |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Brassinin is a phytoalexin isolated from cruciferous vegetables that exhibits anticancer, chemopreventive, antiproliferative and antifungal activities. In lung cancer cells, brassinin inhibits constitutive and IL-6-inducible STAT3 signaling through modulation of PIAS-3 and SOCS-3. It appears that brassinin induces apoptosis in PC-3 prostate cancer cells via the suppression of PI3K/Akt/mTOR/S6K1 signaling. |
Other Notes: | air sensitive |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |