DC_AC50
SIGMA/SML1640 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 497061-48-0
Empirical Formula (Hill Notation): C17H12BrF2N3OS
Molecular Weight: 424.26
Linear Formula: C17H12BrF2N3OS
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to light brown |
form | powder |
InChI | 1S/C17H12BrF2N3OS/c18-10- |
InChI key | DFNOJNBNTVQPCA-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | NC1=C(C(NC2=C(Br)C=C(F)C= |
solubility | DMSO: 10 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | DC_AC50 is an inhibitor of copper trafficking proteins Atox1 and CCS, resulting in a disruption of cellular copper transport. Cancer cells rely more heavily on Atox1 and CCS than normal cells. DC_AC50 blockade of copper trafficking induces cellular oxidative stress, affecting cancer cells more strongly than normal cells, and leading to the inhibition of cancer cell proliferation. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |