NCT-503 Inactive Control
SIGMA/SML1671 - ≥98% (HPLC)
Synonym: N-
CAS Number: 1914971-16-6
Empirical Formula (Hill Notation): C17H21N5S
Molecular Weight: 327.45
Linear Formula: C17H21N5S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C17H21N5S/c1-13-11-14( |
InChI key | ITLPIAAGIQAGRA-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | CC1=CC(NC(N2CCN(C3=CC=NC= |
solubility | DMSO: 5 mg/mL, clear (warmed) |
storage temp. | 2-8°C |
Application: | NCT-503 Inactive Control has been used as a small molecule inhibitor of phosphoglycerate dehydrogenase in neuroblastoma cells. |
Biochem/physiol Actions: | NCT-503 Inactive Control is the inactive control probe for NCT-503, which is an inhibitor of phosphoglycerate dehydrogenase (PHGDH), the enzyme that catalyzes the first, rate-limiting step of glucose-derived serine synthesis. NCT-503 Inactive Control has an IC50 value >57 μM for PHGDH. NCT-503 has an IC50 value of 2.5 μM for PHGDH. NCT-503 Inactive Control is water soluble and has good stability, similar to NCT-503. |
Packaging: | 5, 25 mg in glass bottle |
Recommended products: | The active PHGDH inhibitor, NCT-503, is available from Sigma. To learn more about and purchase NCT-503, click here . |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |