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Ribocil-C

SIGMA/SML1685 - ≥98% (HPLC)

Synonym: 2-[(3S)-1-[[1-(2-Pyrimidinyl)-1H-imidazol-4-yl]methyl]-3-piperidinyl]-6-(2-thienyl)-4(3H)-pyrimidinone

CAS Number: 1825355-56-3
Empirical Formula (Hill Notation): C21H21N7OS
Molecular Weight: 419.50
MDL Number: MFCD29472282
Linear Formula: C21H21N7OS
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1685-5MG 5 mg
 $155.00
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45-SML1685-25MG 25 mg
 $599.00
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assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
SMILES string O=C1NC([C@@]2([H])CCCN(CC3=CN(C4=NC=CC=N4)C=N3)C2)=NC(C5=CC=CS5)=C1
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches.
Biochem/physiol Actions: Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches. Riboswitches are cis regulatory elements present in non-coding RNA that specifically bind to natural ligands to regulate gene expression. Ribocil-C blocks the flavin mononucleotide riboswitch-mediated expression of the ribB gene, which is required for riboflavin biosynthesis, with an IC50 value of 23 nM. Ribocil-C inhibited bacterial cell growth of E. coli MB5746 and bacterial burden in a mouse E. coli septicaemia model of infection.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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