Ribocil-C
SIGMA/SML1685 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 1825355-56-3
Empirical Formula (Hill Notation): C21H21N7OS
Molecular Weight: 419.50
MDL Number: MFCD29472282
Linear Formula: C21H21N7OS
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | O=C1NC([C@@]2([H])CCCN(CC |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Ribocil-C is a potent inhibitor of bacterial riboflavin riboswitches. Riboswitches are cis regulatory elements present in non-coding RNA that specifically bind to natural ligands to regulate gene expression. Ribocil-C blocks the flavin mononucleotide riboswitch-mediated expression of the ribB gene, which is required for riboflavin biosynthesis, with an IC50 value of 23 nM. Ribocil-C inhibited bacterial cell growth of E. coli MB5746 and bacterial burden in a mouse E. coli septicaemia model of infection. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |