ZM323881 hydrochloride
SIGMA/SML1691 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 193000-39-4
Empirical Formula (Hill Notation): C22H18FN3O2 · HCl
Molecular Weight: 411.86
Linear Formula: C22H18FN3O2 · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C22H18FN3O2.ClH/c1-14- |
InChI key | AVRHWGLIYGJSOD-UHFFFAOYSA |
Quality Level | 100 |
solubility | DMSO: 10 mg/mL, clear |
storage condition | desiccated |
storage temp. | 2-8°C |
Biochem/physiol Actions: | ZM323881 is a selective inhibitor of VEGFR-2 with an IC50 value of 2 nM. ZM323881 is selective for VEGFR-2 over VEGFR-1 and other receptor tyrosine kinases including PDGFRβ, FGFR1, EGFR and erbB2. ZM323881 inhibited VEGF-A-induced endothelial cell proliferation with an IC50 value of 8 nM. |
Biochem/physiol Actions: | ZM323881 is also known as (5‐{[7‐(benzyloxy) quinazolin‐4‐yl]amino}‐4‐ |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P301 + P312 + P330 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |