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Temoporfin

SIGMA/SML1707 - ≥90% (HPLC)

Synonym: 3,3′,3′′,3′′′-(7,8-Dihydro-21H,23H-porphine-5,10,15,20-tetrayl)tetrakis-phenol; 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin

CAS Number: 122341-38-2
Empirical Formula (Hill Notation): C44H32N4O4
Molecular Weight: 680.75
Linear Formula: C44H32N4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1707-5MG 5 mg
 $180.00
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45-SML1707-25MG 25 mg
 $578.00
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assay ≥90% (HPLC)
color dark brown to black
form powder
InChI 1S/C44H32N4O4/c49-29-9-1-5-25(21-29)41-33-13-15-35(45-33)42(26-6-2-10-30(50)22-26)37-17-19-39(47-37)44(28-8-4-12-32(52)24-28)40-20-18-38(48-40)43(36-16-14-34(41)46-36)27-7-3-11-31(51)23-27/h1-17,19,21-24,46-47,49-52H,18,20H2
InChI key LYPFDBRUNKHDGX-UHFFFAOYSA-N
Quality Level 100 
solubility DMSO: 2 mg/mL, clear (warmed)
storage temp. −20°C
Biochem/physiol Actions: Temoporfin is a photosensitizer for the photodynamic therapy.
Biochem/physiol Actions: Temoporfin is a photosensitizer for the photodynamic therapy. Temoporfin has been used clinically to treat advanced head and neck squamous cell carcinoma, and is being investigated for use in several other cancers.
General description: Temoporfin/(tetra[m-hydroxyphenyl]chlorin, m-THPC), is a hydrophobic second-generation photosensitizer. It is used in the palliative treatment of patients with advanced head and neck cancer by photodynamic therapy.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥90% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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