RTC13

SIGMA/SML1725 - ≥98% (HPLC)

Synonym: (5Z)-2-Amino-5-[[5-(2-nitrophenyl)-2-furanyl]methylene]-4(5H)-thiazolone; (Z)-2-Amino-5-((5-(2-nitrophenyl)furan-2-yl)methylene)thiazolidin-4-one

CAS Number: 1359825-94-7
Empirical Formula (Hill Notation): C₁₄H₉N₃O₄S
Molecular Weight: 315.30
MDL Number: MFCD00808624
Linear Formula: C₁₄H₉N₃O₄S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1725-5MG	5 mg	$106.00 1/EA	Add To Favorites
45-SML1725-25MG	25 mg	$434.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	yellow to orange
form	powder
InChI	1S/C14H9N3O4S/c15-14-16-13(18)12(22-14)7-8-5-6-11(21-8)9-3-1-2-4-10(9)17(19)20/h1-7H,(H2,15,16,18)/b12-7+
InChI key	CZZAPCPWFCGOCC-KPKJPENVSA-N
Quality Level	100
SMILES string	O=C1NC(S/C1=CC2=CC=C(C3=C([N+]([O-])=O)C=CC=C3)O2)=N
solubility	DMSO: 20 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production from transcripts containing nonsense mutations-generated PTCs, including ataxia-telangiectasia (A-T) mutated in A-T lymphoblastoid cell cultures and dystrophin in mdx Duchenne muscular dystrophy (DMD) mice-derived muscle myotubes.
Biochem/physiol Actions:	RTC13 is a cell-permeable thiazolidinone derivative that promotes ribosomal read-through activity of premature termination codons (PTCs) and effectively restores full-length protein production.
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P301 + P312 + P330
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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