Beraprost sodium
SIGMA/SML1737 - ≥98% (HPLC)
Synonym: 2,3,3a,8b-
CAS Number: 88475-69-8
Empirical Formula (Hill Notation): C24H29O5 · Na
Molecular Weight: 420.47
Linear Formula: C24H29O5 · Na
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C24H30O5.Na/c1-3-4-7-1 |
InChI key | YTCZZXIRLARSET-UEIGIMKUSA |
Quality Level | 100 ![]() |
SMILES string | [H][C@]12[C@](C[C@H](O)[C |
solubility | H2O: 20 mg/mL, clear |
storage condition | protect from light |
storage temp. | −20°C |
Biochem/physiol Actions: | Beraprost sodium is a chemically stable analog of prostacyclin PGI2. As other prostanoids, beraprost is a potent vasodilator and possesses antithrombotic, antiproliferative and anti-inflammatory properties. Beraprost sodium activates prostaglandin I (IP) receptor, which is coupled with Gs proteins and activates adenylate cyclase. It has been studied for the treatment of pulmonary hypertension. |
Biochem/physiol Actions: | Beraprost sodium is used as a therapeutic agent for chronic artery obstructions or primary pulmonary hypertension. In individuals with coronary artery disease, beraprost sodium helps to reduce oxidative stress and developed forearm endothelium dependent vasodilation. |
General description: | Beraprost sodium is an orally active prostacyclin analog. |
Packaging: | 1, 5 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |