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Beraprost sodium

SIGMA/SML1737 - ≥98% (HPLC)

Synonym: 2,3,3a,8b-Tetrahydro-2-hydroxy-1-(3-hydroxy-4-methyl-1-octen-6-ynyl)-1H-cyclopenta(b)benzofuran-5-butanoic acid sodium salt; Procyclin; TRK 100

CAS Number: 88475-69-8
Empirical Formula (Hill Notation): C24H29O5 · Na
Molecular Weight: 420.47
Linear Formula: C24H29O5 · Na
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1737-1MG 1 mg
 $159.00
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45-SML1737-5MG 5 mg
 $641.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C24H30O5.Na/c1-3-4-7-15(2)19(25)13-12-17-20(26)14-21-23(17)18-10-5-8-16(24(18)29-21)9-6-11-22(27)28;/h5,8,10,12-13,15,17,19-21,23,25-26H,6-7,9,11,14H2,1-2H3,(H,27,28);/q;+1/p-1/b13-12+;
InChI key YTCZZXIRLARSET-UEIGIMKUSA-M
Quality Level 100 
SMILES string [H][C@]12[C@](C[C@H](O)[C@H]2/C=C/[C@H](O)C(CC#CC)C)([H])OC3=C1C=CC=C3CCCC([O-])=O.[Na+]
solubility H2O: 20 mg/mL, clear
storage condition protect from light
storage temp. −20°C
Biochem/physiol Actions: Beraprost sodium is a chemically stable analog of prostacyclin PGI2.
Biochem/physiol Actions: Beraprost sodium is a chemically stable analog of prostacyclin PGI2. As other prostanoids, beraprost is a potent vasodilator and possesses antithrombotic, antiproliferative and anti-inflammatory properties. Beraprost sodium activates prostaglandin I (IP) receptor, which is coupled with Gs proteins and activates adenylate cyclase. It has been studied for the treatment of pulmonary hypertension.
Biochem/physiol Actions: Beraprost sodium is used as a therapeutic agent for chronic artery obstructions or primary pulmonary hypertension. In individuals with coronary artery disease, beraprost sodium helps to reduce oxidative stress and developed forearm endothelium dependent vasodilation.
General description: Beraprost sodium is an orally active prostacyclin analog.
Packaging: 1, 5 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 51111800

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