RL648_81

SIGMA/SML1738 - ≥98% (HPLC)

Synonym: Ethyl (2-amino-3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate

CAS Number: 1919050-87-5
Empirical Formula (Hill Notation): C₁₇H₁₇F₄N₃O₂
Molecular Weight: 371.33
Linear Formula: C₁₇H₁₇F₄N₃O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML1738-5MG	5 mg	$159.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C17H17F4N3O2/c1-2-26-16(25)24-13-8-7-12(14(18)15(13)22)23-9-10-3-5-11(6-4-10)17(19,20)21/h3-8,23H,2,9,22H2,1H3,(H,24,25)
InChI key	MVSMZQRRMPUGHI-UHFFFAOYSA-N
Quality Level	100
SMILES string	NC1=C(NC(OCC)=O)C=CC(NCC2=CC=C(C(F)(F)F)C=C2)=C1F
solubility	DMSO: 25 mg/mL, clear
storage temp.	room temp

Biochem/physiol Actions:	Ethyl (2-amino-3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate (RL648_81) is 15 times more effective and more selective than retigabine, an anticonvulsant. RL648_81 helps to treat or inhibit neurologic disorders linked with neuronal hyperexcitability.
Biochem/physiol Actions:	RL648_81 is a KCNQ2/3 channel activator.
Biochem/physiol Actions:	RL648_81 is a selective and potent KCNQ2/3 channel activator.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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