Narasin Ready Made Solution
SIGMA/SML1749 - 1 mg/ml in DMSO
Synonym: (2R)
CAS Number: 55134-13-9
Empirical Formula (Hill Notation): C43H72O11
Molecular Weight: 765.03
Linear Formula: C43H72O11
Product Type: Chemical
biological source | Streptomyces aureofaciens |
concentration | 1 mg/ml in DMSO |
form | solution |
InChI | 1S/C43H72O11/c1-12-30(35( |
InChI key | VHKXXVVRRDYCIK-CWCPJSEDSA |
Quality Level | 200 ![]() |
shipped in | dry ice |
storage temp. | −20°C |
Biochem/physiol Actions: | Narasin is a growth-promoting ionophoric antibacterial agent for Enterococci, specifically Enterococcus faecium and Enterococcus faecalis. Narasin inhibits coccidial infection in poultry and mammals and is used in studies involving sodium calcium ion exchange. In addition, Narasin inhibits Dengue virus (DENV) at the post-entry stage of viral replication during DENV infection. The inhibition of DENV involves a non-cytotoxic mechanism, therefore, Narasin can be possibly considered as therapeutic agent against DENV infection. A dose dependent curve (0.01-5 μM) showed that Narasin has 50% inhibitory concentration at less than 1 μM against all four serotypes of DENV. The IC50 (μM) of Narasin against four different DENV serotypes was 0.05-0.65 μM. |
Other Notes: | Narasin solution is provided at 1.307 mM (1 mg/ml). Typical final concentration for use in cell culture is 0.01-5 μM. Stable at –20 °C for at least 2 years. |
WGK Germany | WGK 1 |
Flash Point(F) | 188.6 °F - closed cup |
Flash Point(C) | 87 °C - closed cup |
Storage Temp. | −20°C |
UNSPSC | 12352200 |