LF3
SIGMA/SML1752 - ≥98% (HPLC)
Synonym: N-
CAS Number: 664969-54-4
Empirical Formula (Hill Notation): C20H24N4O2S2
Molecular Weight: 416.56
Linear Formula: C20H24N4O2S2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | S=C(NC1=CC=C(S(N)(=O)=O)C |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | LF3 is a potent inhibitor of Wnt/β-catenin signaling that suppresses cancer cells motility, cell-cycle progression, and the overexpression of Wnt target genes. LF3 is a potent and specific antagonist of the interaction between β-catenin and the transcription factor TCF4. LF3 blocks self-renewal of cancer stem cells. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H315 - H319 |
Precautionary statements | P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |