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BAM15

SIGMA/SML1760 - ≥98% (HPLC)

Synonym: BAM 15; N5,N6-bis(2-Fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine

CAS Number: 210302-17-3
Empirical Formula (Hill Notation): C16H10F2N6O
Molecular Weight: 340.29
MDL Number: MFCD00373912
Linear Formula: C16H10F2N6O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1760-5MG 5 mg
 $125.00
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45-SML1760-25MG 25 mg
 $511.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1760-5MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24)
InChI key OEGJBRZAJRPPHL-UHFFFAOYSA-N
Quality Level 100 
SMILES string FC(C=CC=C1)=C1NC2=NC3=NON=C3N=C2NC4=CC=CC=C4F
solubility DMSO: 20 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: BAM15 increases mitochondrial respiration rate and is also found to be less cytotoxic compared to other protonophore uncouplers such as carbonyl cyanide p-trifluoromethoxyphenylhydrazone. Hindered oncogenic MAPK (mitogen-activated protein kinase ) signaling leads to BAM15 induced mitochondrial apoptotic pathway activation.
Biochem/physiol Actions: BAM15 is a cell penetrant and potent uncoupler of oxidative phosphorylation in mitochondria that that does not depolarizes the plasma membrane. BAM15 protects mice from acute renal ischemic-reperfusion injury.
Biochem/physiol Actions: BAM15 is a cell penetrant and potent uncoupler of oxidative phosphorylation in mitochondria.
Packaging: 5, 25 mg in glass bottle
Hazard statements H413
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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