Synonym: 9-(1,3-Benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-naphtho[2,3-c]furan-1(3H)-one; NSC 309691
CAS Number: 22055-22-7
Empirical Formula (Hill Notation): C21H16O7
Molecular Weight: 380.35
MDL Number: MFCD00808222
Linear Formula: C21H16O7
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to light brown |
form |
powder |
InChI |
1S/C21H16O7/c1-24-15-6-11-12(7-16(15)25-2)20(22)13-8-26-21(23)19(13)18(11)10-3-4-14-17(5-10)28-9-27-14/h3-7,22H,8-9H2,1-2H3 |
InChI key |
VMEJANRODATDOF-UHFFFAOYSA-N |
Quality Level |
100 |
SMILES string |
OC1=C2C(C(OC2)=O)=C(C3=CC=C(OCO4)C4=C3)C5=CC(OC)=C(OC)C=C51 |
solubility |
DMSO: 5 mg/mL, clear (warmed) |
storage temp. |
2-8°C |
Application: |
Diphyllin has been used to study its antibacterial and antibiofilm activities against fish pathogens. |
Biochem/physiol Actions: |
Diphyllin has shown potential to be used in a novel treatment for bone problems characterized by excessive resorption. |
Biochem/physiol Actions: |
Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities. It is a potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts. |
General description: |
Diphyllin, a major glycoside compound, is a plant-derived lignan. It is present in Cleistanthus collinus. |
Packaging: |
5, 25 mg in glass bottle |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |