Sparstolonin B
SIGMA/SML1767 - ≥98% (HPLC)
Synonym: 4,10-
CAS Number: 1259330-61-4
Empirical Formula (Hill Notation): C15H8O5
Molecular Weight: 268.22
Linear Formula: C15H8O5
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 |
SMILES string | OC(C=C1)=CC2=C1OC3=C4C(C( |
solubility | DMSO: 10 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Potent TLR2 and TLR4 antagonist that exhibits anti-inflammatory and anti-viral (anti-HIV) properties |
Biochem/physiol Actions: | Sparstolonin B (SsnB) is a polyphenol. It has a structural features similar to xanthone and isocoumarin. SsnB exerts anti-inflammatory properties on mouse and human macrophages. SsnB can significantly reduce hypoxia–reoxygenation-ind |
Biochem/physiol Actions: | Sparstolonin B (SsnB), an isocoumarin isolated from Sparganium stoloniferum and Scirpus yagara, is a potent TLR2 and TLR4 antagonist that exhibits anti-inflammatory and anti-viral (anti-HIV) properties. Sparstolonin B inhibits LPS induced inflammation in 3T3- L1 adipocytes, and reduces the body weight of rats fed with high fat diet. Sparstolonin B mitigates inflammation in nonalcoholic steatohepatitis (NASH) in mice model. |
Packaging: | 5, 25 mg in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |