Ximelagatran
SIGMA/SML1768 - ≥98% (HPLC)
Synonym: H 376/95; N-
CAS Number: 192939-46-1
Empirical Formula (Hill Notation): C24H35N5O5
Molecular Weight: 473.57
Linear Formula: C24H35N5O5
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C24H35N5O5/c1-2-34-20( |
InChI key | ZXIBCJHYVWYIKI-PZJWPPBQSA |
Quality Level | 100 ![]() |
SMILES string | N/C(C1=CC=C(CNC([C@@H]2CC |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | It inhibits both clot-bound and free thrombin. It is quickly absorbed by the small intestine and converted to its active dipeptide drug form, Melagatran. Melagatran associates with the arginine side pocket in thrombin and inactivates it. Ximelagatran has a half-life of 4-5 hours. It is administered orally twice a day. |
Biochem/physiol Actions: | Ximelagatran is orally active, selective and potent direct thrombin inhibitor. Ximelagatran is a prodrug of thrombin inhibitor melagatran. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |