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PhiKan083 hydrochloride

SIGMA/SML1770 - ≥98% (HPLC)

Synonym: 9-Ethyl-N-methyl-9H-Carbazole-3-methanamine hydrochloride; PK-083 hydrochloride; PK083 hydrochloride; PhiKan-083 hydrochloride

CAS Number: 1050480-30-2
Empirical Formula (Hill Notation): C16H18N2 · HCl
Molecular Weight: 274.79
MDL Number: MFCD07168924
Linear Formula: C16H18N2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1770-5MG 5 mg
 $94.00
1/EA		 Add To Favorites
45-SML1770-25MG 25 mg
 $380.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI key IXWVUPURFWFRNE-UHFFFAOYSA-N
Quality Level 100 
SMILES string CNCC1=CC2=C(C=C1)N(CC)C3=C2C=CC=C3.[H]Cl
solubility H2O: 2 mg/mL, clear
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Mutant p53 stabilizer
Biochem/physiol Actions: PhiKan083 is a small molecule that binds within a cavity on the surface of Y220C-mutated p53. This mutation, which is not involved in DNA interaction, causes a destabilization of the protein. PhiKan083 binding acts to stabilize the mutant p53 and slow the rate of denaturation.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319
Precautionary statements P305 + P351 + P338
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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