BAY-876
SIGMA/SML1774 - ≥98% (HPLC)
Synonym: N4-
CAS Number: 1799753-84-6
Empirical Formula (Hill Notation): C24H16F4N6O2
Molecular Weight: 496.42
Linear Formula: C24H16F4N6O2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | FC1=CC=C2C(N=C(C(N)=O)C=C |
solubility | DMSO: 25 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. It had an IC50 value of 2 nM in vitro and inhibited glucose uptake by Hela-MaTu cells with an IC50 value of 3.2 nM. BAY-876 was at least 130-fold selective for GLUT1 relative to GLUT2, GLUT3, GLUT4 and a panel of 18 kinases and 68 proteins. For full characterization details, please visit the BAY-876 probe summary ![]() ![]() BAY-588 is the negative control for the active probe, BAY-876. BAY-588 is available from Sigma. To learn more about and purchase BAY-588, click here ![]() To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc ![]() |
Features and Benefits: | BAY-876 is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC ![]() |
Features and Benefits: | This compound is a featured product for Nitric Oxide & Cell Stress research. Click here ![]() ![]() |
Packaging: | 5, 25 mg in glass bottle |
Recommended products: | BAY-588 is used as a negative control and is available from Sigma. To learn more about and purchase BAY-588, click here ![]() |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |