Synonym: 4-[4-(Dimethylamino)phenyl]-N-(3,5-dimethylphenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxamide
CAS Number: 537679-57-5
Empirical Formula (Hill Notation): C22H26N4O2
Molecular Weight: 378.47
Linear Formula: C22H26N4O2
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI key |
JQVNMIXFWKEYQJ-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
O=C1NC(C2=CC=C(N(C)C)C=C2)C(C(NC3=CC(C)=CC(C)=C3)=O)=C(C)N1 |
| solubility |
DMSO: 5 mg/mL, clear (warmed) |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
BTI-A-404 is a potent and selective competitive inverse agonist of human GPR43 (FFAR2). |
| Biochem/physiol Actions: |
BTI-A-404 is a potent and selective competitive inverse agonist of human GPR43 (GPR43/Free Fatty Acid Receptor 2, FFAR2) that increases the cyclic AMP level and regulates and reduces acetate-induced cytoplasmic Ca2+ level. BTI-A-404 regulates the downstream signaling pathways of GPR43, including ERK, p38 MAPK, and NF-KB. BTI-A-404 stimulates GLP-1 release. |
| Packaging: |
5, 25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
51111800 |
