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Tariquidar

SIGMA/SML1790 - ≥98% (HPLC)

Synonym: N-[2-[[[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarboxamide; XR 9576; XR9576

CAS Number: 206873-63-4
Empirical Formula (Hill Notation): C38H38N4O6
Molecular Weight: 646.73
MDL Number: MFCD09837824
Linear Formula: C38H38N4O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1790-5MG 5 mg
 $159.00
1/EA		 Add To Favorites
45-SML1790-25MG 25 mg
 $639.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SML1790-5MG.

 

assay ≥98% (HPLC)
color white to light brown
form powder
InChI 1S/C38H38N4O6/c1-45-33-18-25-14-16-42(23-28(25)19-34(33)46-2)15-13-24-9-11-29(12-10-24)40-38(44)30-20-35(47-3)36(48-4)21-32(30)41-37(43)27-17-26-7-5-6-8-31(26)39-22-27/h5-12,17-22H,13-16,23H2,1-4H3,(H,40,44)(H,41,43)
InChI key LGGHDPFKSSRQNS-UHFFFAOYSA-N
Quality Level 100 
SMILES string O=C(C1=CC(OC)=C(OC)C=C1NC(C2=CC(C=CC=C3)=C3N=C2)=O)NC(C=C4)=CC=C4CCN5CC6=CC(OC)=C(OC)C=C6CC5
solubility DMSO: 10 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Specific inhibitor of MDR-1 (P-gp)
Biochem/physiol Actions: Tariquidar is a non-competitive inhibitor. It is used as a potential agent for checking the role of P-glycoprotein inhibition in cancer. Tariquidar also has an ability to enhance drug exposure in drug-resistant cancers.
Biochem/physiol Actions: Tariquidar is a potent MDR1 (P-gp, P-glycoprotein) inhibitor. Tariquidar reverses multidrug resistance (MDR) by inhibiting MDR1-mediated drug efflux.
Packaging: 5, 25 mg in glass bottle
Hazard statements H413
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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