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AM4113

SIGMA/SML1804 - ≥98% (HPLC)

Synonym: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

CAS Number: 614726-85-1
Empirical Formula (Hill Notation): C17H12Cl3N3O
Molecular Weight: 380.66
Linear Formula: C17H12Cl3N3O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML1804-5MG 5 mg
$114.00
1/EA
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45-SML1804-25MG 25 mg
$0.00
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assay ≥98% (HPLC)
color white to brown
form powder
Quality Level 100 
SMILES string ClC1=CC(Cl)=C(N2C(C3=CC=C(Cl)C=C3)=C(C)C(C(N)=O)=N2)C=C1
solubility DMSO: 2 mg/mL, clear (warmed)
storage temp. 2-8°C
Biochem/physiol Actions: AM4113 is a Cannabinoid CB-1 neutral antagonist. AM4113 reduced reward and reinstatement of drug-seeking behavior, reducing cue-induced reinstatement in monkeys trained to self-administer cocaine.
Biochem/physiol Actions: AM4113 is a pyrazole-3-carboxamide analog of rimonabant (SR141716A). In rats, it suppresses food-motivated behaviors and food intake, thereby reducing weight gain without inducing nausea. AM4113 has poor oral bioavailability. Therefore, it may not act as an effective appetite suppressant in humans.
Packaging: 5, 25 mg in glass bottle
Hazard statements H413
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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