Ani9
SIGMA/SML1813
Synonym: (4-
CAS Number: 356102-14-2
Empirical Formula (Hill Notation): C17H17ClN2O3
Molecular Weight: 332.78
Linear Formula: C17H17ClN2O3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | CC1=C(OCC(NN=CC2=C(OC)C=C |
solubility | DMSO: 25 mg/mL, clear |
storage temp. | 2-8°C |
Application: | Ani9 has been used to find out the inappropriate modulation of the membrane protein functions that are involved in the 198 ADGRG2- or Gq-mediated regulation of fluid reabsorption in the efferent ductules. |
Biochem/physiol Actions: | 2-(4-chloro-2-methylpheno |
Biochem/physiol Actions: | Ani9 is a potent and highly selective anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A) inhibitor that completely inhibited ANO1 chloride current with submicromolar potency. Ani9 does not affect the intracellular calcium signaling and CFTR chloride channel activity. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |