ADX71743
SIGMA/SML1829 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 1431641-29-0
Empirical Formula (Hill Notation): C17H19NO2
Molecular Weight: 269.34
MDL Number: MFCD30474715
Linear Formula: C17H19NO2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 |
SMILES string | CC1=CC(C)=CC=C1C2CC(OC(CC |
solubility | DMSO: 5 mg/mL, clear (warmed) |
storage temp. | −20°C |
Biochem/physiol Actions: | ADX71743 is a brain-penetrant, selective and potent negative allosteric modulator of metabotropic glutamate receptor 7 (mGlu7). In one study ADX71743 exhibited an anxiolytic-like profile in rat and mouse models without causing impairment of locomotor activity. In another study it induced absence epileptic seizures and lethargy. |
Biochem/physiol Actions: | ADX71743 is known to negatively regulate the effect of mGlu7 (metabotropic glutamate receptor subtype 7), which is associated with a number of anxiety disorders. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |