ADX71743

SIGMA/SML1829 - ≥98% (HPLC)

Synonym: 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydrobenzo[d]oxazol-4(5H)-one

CAS Number: 1431641-29-0
Empirical Formula (Hill Notation): C₁₇H₁₉NO₂
Molecular Weight: 269.34
MDL Number: MFCD30474715
Linear Formula: C₁₇H₁₉NO₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML1829-25MG	25 mg	$434.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI key	CPKZCQHJDFSOJT-UHFFFAOYSA-N
Quality Level	100
SMILES string	CC1=CC(C)=CC=C1C2CC(OC(CC)=N3)=C3C(C2)=O
solubility	DMSO: 5 mg/mL, clear (warmed)
storage temp.	−20°C

Biochem/physiol Actions:	ADX71743 is a brain-penetrant, selective and potent negative allosteric modulator of metabotropic glutamate receptor 7 (mGlu7).
Biochem/physiol Actions:	ADX71743 is a brain-penetrant, selective and potent negative allosteric modulator of metabotropic glutamate receptor 7 (mGlu7). In one study ADX71743 exhibited an anxiolytic-like profile in rat and mouse models without causing impairment of locomotor activity. In another study it induced absence epileptic seizures and lethargy.
Biochem/physiol Actions:	ADX71743 is known to negatively regulate the effect of mGlu7 (metabotropic glutamate receptor subtype 7), which is associated with a number of anxiety disorders.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352200

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.