KYA1797K potassium salt

SIGMA/SML1831 - ≥98% (HPLC)

Synonym: (5Z)-5-[[5-(4-Nitrophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidinepropanoic acid potassium salt; (Z)-3-(5-((5-(4-nitrophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid potassium salt; KYA1797 potassium salt

CAS Number: 1956356-56-1
Empirical Formula (Hill Notation): C₁₇H₁₁KN₂O₆S₂
Molecular Weight: 442.51
Linear Formula: C₁₇H₁₁KN₂O₆S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1831-5MG	5 mg	$114.00 1/EA	Add To Favorites
45-SML1831-25MG	25 mg	$464.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	orange to dark red
form	powder
Quality Level	100
SMILES string	[O-]C(CCN1C(/C(SC1=S)=C/C2=CC=C(C3=CC=C([N+]([O-])=O)C=C3)O2)=O)=O.[K+]
solubility	DMSO: 2 mg/mL, clear (warmed)
storage temp.	2-8°C

Biochem/physiol Actions:

KYA1797K is an inhibitor of both Wnt/β-catenin and Ras pathways. It binds to the axin regulators of the G-protein signaling (RGS) domain enhancing formation of the β-catenin destruction complex and inducing activation GSK3β, which results in phosphorylation and subsequent degradation of both β-catenin and K-Ras. KYA1797K was show to suppress tumor growth and progression in mouse xenografts of CRC cells that had APC and K-Ras mutations.

Packaging:

5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

To Order From a Quote