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YK-3-237

SIGMA/SML1840

Synonym: B-[2-methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]-boronic acid

CAS Number: 1215281-19-8
Empirical Formula (Hill Notation): C19H21BO7
Molecular Weight: 372.18
Linear Formula: C19H21BO7
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1840-5MG 5 mg
 $106.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
solubility DMSO: 25 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: YK-3-237 is an activator of sirtuin-1 (SIRT1).
Biochem/physiol Actions: YK-3-237 is an activator of sirtuin-1 (SIRT1). YK-3-237 showed anti-proliferative activity toward triple-negative breast cancer, inducing G2/M cell cycle arrest and apoptosis. In a study on renal fibrosis, YK-3-237 caused enhanced expression of α-SMA and fibronectin, suggesting that long-term use of SIRT1 activators may increase the risk or progression of chronic kidney disease.
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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