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PCS1055 dihydrochloride

SIGMA/SML1848 - ≥98% (HPLC)

Synonym: 6,7-Dihydro-N-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-amine dihydrochloride

CAS Number: 361979-40-0
Empirical Formula (Hill Notation): C27H32N4 · 2HCl
Molecular Weight: 485.49
Linear Formula: C27H32N4 · 2HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1848-25MG 25 mg
 $464.00
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assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
SMILES string [H]Cl.[H]Cl.C12=C(N=NC(NCCC3CCN(CC4=CC=CC=C4)CC3)=C2)C5=C(C=CC=C5)CCC1
solubility H2O: 5 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: PCS1055 is a potent and selective muscarinic M4 acetylcholine receptor competitive antagonist that exhibits >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor. PCS1055 was originally described as a potent electric eel AChE inhibitor (IC50 = 22 nM) and less potent at human AChE (IC50 = 120 nM).
Packaging: 5, 25 mg in glass bottle
Hazard statements H413
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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