8-Aminoguanosine
SIGMA/SML1852 - ≥98% (HPLC)
Synonym: 2,8-Diamino-inosine; NSC 90390
CAS Number: 3868-32-4
Empirical Formula (Hill Notation): C10H14N6O5
Molecular Weight: 298.26
Linear Formula: C10H14N6O5
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to brown |
form | powder |
InChI | 1S/C10H14N6O5/c11-9-14-6- |
InChI key | FNXPTCITVCRFRK-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | NC1=NC(C2=C(N1)N([C@@H]3O |
solubility | DMSO: 1 mg/mL, clear (warmed) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | 8-Aminoguanosine is known to stimulate diuresis, natriuresis, glucosuria and antikaliuresis. It is an analog of guanosine, that can block purine nucleoside phosphorylase, in vitro and in intact lymphoid cells. 8-aminoguanosine triphosphate can be used to block GTP (guanosine triphosphate) cyclohydrolase I from human liver and Escherichia coli. |
Biochem/physiol Actions: | 8-Aminoguanosine, a guanosine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic that increased sodium excretion by 26.2-fold and decrease potassium excretion by 69.1%. 8-Aminoguanosine increases glucose excretion by 12.2-fold. Also 8-Aminoguanosine suppressed deoxycorticosterone/salt- |
Packaging: | 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |