Synonym: 1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione; AQ4N dihydrochloride
CAS Number: 252979-56-9
Empirical Formula (Hill Notation): C22H28N4O6 · 2HCl
Molecular Weight: 517.40
MDL Number: MFCD19690955
Linear Formula: C22H28N4O6 · 2HCl
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
blue |
form |
powder |
Quality Level |
100 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
O=C1C2=C(C(NCC[N+](C)([O-])C)=CC=C2NCC[N+]([O-])(C)C)C(C3=C(O)C=CC(O)=C31)=O.[H]Cl.[H]Cl |
solubility |
H2O: 3 mg/mL, clear (warmed) |
storage condition |
desiccated |
storage temp. |
2-8°C |
Application: |
Banoxantrone dihydrochloride has been used as an organic ligand during a self-assembled metal-organic coordinated nanoparticle (Cu–OCNP/Lap) synthesis. It has also been used for the preparation of supramolecularly functionalized graphene oxide for hypoxia-activated chemotherapy of cancer. |
Biochem/physiol Actions: |
Banoxantrone (AQ4N) is a hypoxia-activated prodrug of topoisomerase II inhibitor AQ4 (Bioreductive AQ4 precursor). |
Biochem/physiol Actions: |
Banoxantrone dihydrochloride enhances the anti-tumor effect caused by radiation. |
Packaging: |
5, 25 mg in glass bottle |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |