J104129 fumarate
SIGMA/SML1861 - ≥98% (HPLC)
Synonym: (αR)-α-Cyclopentyl-α-hydroxy-N-[1-(4-methyl-3-penten-1-yl)-4-piperidinyl]-Benzeneacetamide fumarate; J-104129
CAS Number: 257603-40-0
Empirical Formula (Hill Notation): C24H36N2O2 · C4H4O4
Molecular Weight: 500.63
MDL Number: MFCD09753272
Linear Formula: C24H36N2O2 · C4H4O4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
optical activity | [α]/D -6 to -8°, c = 1 in methanol |
Quality Level | 100 ![]() |
SMILES string | O=C(O)/C=C/C(O)=O.CC(C)=C |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | J104129 is a muscarinic M3 receptor antagonist greater than 100-fold selectivity for M3 over M2 receptors. Its Ki for M3 receptors = 4.2 nM compared to a Ki of 490 nM for M2 receptors. J-104129 showed potent bronchodilator activity in animal studies. |
Packaging: | 5, 25 mg in glass bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |