DM-NOFD

SIGMA/SML1874 - ≥98% (HPLC)

Synonym: Dimethyl N-oxalyl-D-phenylalanine; N-(2-Methoxy-2-oxoacetyl)-D-phenylalanine methyl ester; N-Oxalyl-D-phenylalanine dimethyl ester

CAS Number: 865488-53-5
Empirical Formula (Hill Notation): C₁₃H₁₅NO₅
Molecular Weight: 265.26
Linear Formula: C₁₃H₁₅NO₅
Product Type: Chemical

assay	≥98% (HPLC)
color	, colorless to dark yellow
form	oil
InChI	1S/C13H15NO5/c1-18-12(16)10(14-11(15)13(17)19-2)8-9-6-4-3-5-7-9/h3-7,10H,8H2,1-2H3,(H,14,15)/t10-/m1/s1
InChI key	CAUUPQLNYYFMOQ-SNVBAGLBSA-N
Quality Level	100
SMILES string	O=C(C(N[C@H](CC1=CC=CC=C1)C(OC)=O)=O)OC
storage temp.	2-8°C

Biochem/physiol Actions:	DM-NOFD is a cell penetrant, prodrug of NOFD a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF).
Biochem/physiol Actions:	DM-NOFD is a cell penetrant, prodrug of NOFD a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF). DM-NOFD efficiently reduces HIF1a CAD (C-terminal activating domain) hydroxylation in MCF-7 cells.
General description:	Dimethyl N-oxalyl-D-phenylalanine (DM-NOFD) is a small FIH (factor-inhibiting) inhibitor molecule.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable