Tadalafil
SIGMA/SML1877 - ≥98% (HPLC)
Synonym: (6R,12aR)
CAS Number: 171596-29-5
Empirical Formula (Hill Notation): C22H19N3O4
Molecular Weight: 389.40
Linear Formula: C22H19N3O4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C22H19N3O4/c1-24-10-19 |
InChI key | WOXKDUGGOYFFRN-IIBYNOLFSA |
optical activity | [α]/D +68 to +78°, c = 1 in chloroform-d |
Quality Level | 100 ![]() |
solubility | DMSO: 20 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Tadalafil is a potent, selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) used to treat erectile dysfunction, pulmonary hypertension, and benign prostatic hyperplasia (BPH). This β-carboline-based drug has a long elimination half-life of about 18 hours. |
Packaging: | 10, 50 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |