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Tadalafil

SIGMA/SML1877 - ≥98% (HPLC)

Synonym: (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione; ICI-351

CAS Number: 171596-29-5
Empirical Formula (Hill Notation): C22H19N3O4
Molecular Weight: 389.40
Linear Formula: C22H19N3O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1877-10MG 10 mg
 $86.00
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45-SML1877-50MG 50 mg
 $291.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
InChI key WOXKDUGGOYFFRN-IIBYNOLFSA-N
optical activity [α]/D +68 to +78°, c = 1 in chloroform-d
Quality Level 100 
SMILES string N21[C@H](Cc3c4c([nH]c3[C@H]2c5cc6c(cc5)OCO6)cccc4)C(=O)N(CC1=O)C
solubility DMSO: 20 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Tadalafil is a potent, selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) used to treat erectile dysfunction, pulmonary hypertension, and benign prostatic hyperplasia (BPH).
This β-carboline-based drug has a long elimination half-life of about 18 hours.
Packaging: 10, 50 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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