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A-395N

SIGMA/SML1879 - ≥98% (HPLC)

Synonym: (3S,4R)-1-Benzyl-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine; (3S,4R)-{1-Benzyl-4-[4-(4-methanesulfonyl-piperazin-1-yl)-phenyl]-pyrrolidin-3-yl}-dimethyl-amine

Empirical Formula (Hill Notation): C24H34N4O2S
Molecular Weight: 442.62
Linear Formula: C24H34N4O2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1879-5MG 5 mg
 $142.00
1/EA		 Add To Favorites
45-SML1879-25MG 25 mg
 $330.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
optical activity [α]/D +1.0 to +3.0°, c = 1 in chloroform-d
Quality Level 100 
solubility DMSO: 10 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: A-395N is a control probe for A-395 , which is a chemical probe for polycomb protein EED. A-395 is a potent and selective chemical probe for the polycomb protein EED (embryonic ectoderm development), an essential component of Polycomb repressive complex 2 (PRC2), involved in transcriptional repression through methylation of histone H3K27. A-395N is structurally similar, but exhibits no activity in the biochemical and cellular assays, so is an ideal control compound. For characterization details of the active probe, A-395, please visit the A-395 probe summary  on the Structural Genomics Consortium (SGC) website.

A-395, the active enantiomer, is available from Sigma. To learn more about and purchase A-395, click here .

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc 
Features and Benefits: A-395N is a negative control for A-395, an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC .
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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