VPC-13566

SIGMA/SML1886 - ≥98% (HPLC)

Synonym: 2-(7-Methyl-1H-indol-3-yl)quinoline

CAS Number: 218464-59-6
Empirical Formula (Hill Notation): C₁₈H₁₄N₂
Molecular Weight: 258.32
Linear Formula: C₁₈H₁₄N₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-SML1886-5MG	5 mg	$116.00 1/EA		Add To Favorites
45-SML1886-25MG	25 mg	$467.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI key	FPKBNOVQNMJTEJ-UHFFFAOYSA-N
Quality Level	100
SMILES string	CC1=CC=CC2=C1NC=C2C3=NC4=CC=CC=C4C=C3
solubility	DMSO: 20 mg/mL, clear
storage temp.	2-8°C

Biochem/physiol Actions:	VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor.
Biochem/physiol Actions:	VPC-13566 is Binding Function 3 (BF3)-specific inhibitor of the androgen receptor. VPC-13566 potently inhibits AR transcriptional activity by displacement of the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines including an enzalutamide-resistant cell line and inhibits the growth of AR-dependent prostate cancer xenograft in mice.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	51111800

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