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SYP-5

SIGMA/SML1894 - ≥98% (HPLC)

Synonym: (2E)-1-(5-Hydroxy-2-2-dimethyl-2H-1-benzopyran-6-yl)-3-(2-thienyl)-2-propen-1-one; (E)-1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(thio-phen-2-yl)prop-2-en-1-one

CAS Number: 1384268-04-5
Empirical Formula (Hill Notation): C18H16O3S
Molecular Weight: 312.38
MDL Number: MFCD30534394
Linear Formula: C18H16O3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1894-5MG 5 mg
 $78.40
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assay ≥98% (HPLC)
color white to beige
form powder
InChI key OMVURDVBYIJCOI-FNORWQNLSA-N
Quality Level 100 
SMILES string OC1=C(C=CC(C)(C)O2)C2=CC=C1C(/C=C/C3=CC=CS3)=O
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: SYP-5 is potent and selective inhibitor of HIF-1 activity that decreases HIF-1α and HIF-1β protein levels under hypoxic condition. SYP-5 inhibits tumor cell migration and invasion, as well as tumor angiogenesis.
Biochem/physiol Actions: SYP-5 is potent and selective inhibitor of HIF-1 activity.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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