Iguratimod

SIGMA/SML1898 - ≥98% (HPLC)

Synonym: 3-Formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one; IGU; N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide; N-[3-(Formylamino)-4-oxo-6-phenoxy-4H-1-benzopyran-7-yl]methanesulfonamide; T-614

CAS Number: 123663-49-0
Empirical Formula (Hill Notation): C₁₇H₁₄N₂O₆S
Molecular Weight: 374.37
MDL Number: MFCD00882374
Linear Formula: C₁₇H₁₄N₂O₆S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-SML1898-5MG	5 mg	$116.00 1/EA	Add To Favorites
45-SML1898-25MG	25 mg	$372.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C17H14N2O6S/c1-26(22,23)19-13-8-15-12(17(21)14(9-24-15)18-10-20)7-16(13)25-11-5-3-2-4-6-11/h2-10,19H,1H3,(H,18,20)
InChI key	ANMATWQYLIFGOK-UHFFFAOYSA-N
Quality Level	100
SMILES string	O=S(NC1=CC(OC=C(NC([H])=O)C2=O)=C2C=C1OC3=CC=CC=C3)(C)=O
solubility	DMSO: 5 mg/mL, clear (warmed)
storage temp.	2-8°C

Biochem/physiol Actions:	Iguratimod (T-614) is an orally active anti-inflammatory compound that inhibits NF-kappaB (NF-KB) p65 subunit (RelA) phosphorylation and nuclear translocation (30 μg/mL against 10 ng/mL TNF-α; human synovial cells) without affecting IKBα degradation.
Biochem/physiol Actions:	Iguratimod (T-614) is an orally active anti-inflammatory compound that inhibits NF-kappaB p65 subunit (RelA) phosphorylation and nuclear translocation.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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