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IC87201

SIGMA/SML1910 - ≥98% (HPLC)

Synonym: 2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichloro-phenol; 2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol; IC 87201; IC-87201; Phenol, 2-[(1H-benzotriazol-6-ylamino)methyl]-4,6-dichloro-

CAS Number: 866927-10-8
Empirical Formula (Hill Notation): C13H10Cl2N4O
Molecular Weight: 309.15
Linear Formula: C13H10Cl2N4O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1910-5MG 5 mg
 $78.70
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assay ≥98% (HPLC)
color white to brown
form powder
InChI 1S/C13H10Cl2N4O/c14-8-3-7(13(20)10(15)4-8)6-16-9-1-2-11-12(5-9)18-19-17-11/h1-5,16,20H,6H2,(H,17,18,19)
InChI key QEHVTUCLCBXQIC-UHFFFAOYSA-N
Quality Level 100 
SMILES string Clc1c(c(cc(c1)Cl)CNc2cc3[nH]nnc3cc2)O
solubility DMSO: 5 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures.
Biochem/physiol Actions: IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures. IC87201 exhibits analgesic properties in mice pain models. Contrary to NMDA receptor antagonists nNOS/PSD-95 protein-protein interaction inhibitors spared source memory, spatial memory, and motor function in rats.
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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