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ML364

SIGMA/SML1920 - ≥98% (HPLC)

Synonym: 2-(4-Methylphenylsulfonamido)-N-(4-phenylthiazol-2-yl)-4-(trifluoromethyl)benzamide; 2-[[(4-Methylphenyl)sulfonyl]amino]-N-(4-phenyl-2-thiazolyl)-4-(trifluoromethyl)-benzamide

CAS Number: 1991986-30-1
Empirical Formula (Hill Notation): C24H18F3N3O3S2
Molecular Weight: 517.54
Linear Formula: C24H18F3N3O3S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1920-5MG 5 mg
 $98.40
1/EA		 Add To Favorites
45-SML1920-25MG 25 mg
 $318.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI key QZUGMNXETPARLI-UHFFFAOYSA-N
Quality Level 100 
SMILES string FC(F)(F)c1cc(c(cc1)C(=O)Nc3[s]cc(n3)c4ccccc4)N[S](=O)(=O)c2ccc(cc2)C
solubility DMSO: 20 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: ML364 is a potent and specific inhibitor of the deubiquitinase USP2 that induces cellular Cyclin D1 degradation in HCT116 colorectal cancer cells, followed by cell cycle arrest and apoptosis. Also, ML364 inhibits homologous recombination (HR)-mediated DNA repair.
Biochem/physiol Actions: Potent and specific inhibitor of the deubiquitinase USP2
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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