GAT211
SIGMA/SML1926 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 102704-40-5
Empirical Formula (Hill Notation): C22H18N2O2
Molecular Weight: 342.39
MDL Number: MFCD02165420
Linear Formula: C22H18N2O2
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C22H18N2O2/c25-24(26)1 |
| InChI key | OHZDCJJHWPHZJD-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | O=[N+]([O-])CC(C1=CC=CC=C |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | GAT211 is a positive allosteric modulator (PAM) of cannabinoid CB1 receptor signaling. |
| Biochem/physiol Actions: | GAT211 is a positive allosteric modulator (PAM) of cannabinoid CB1 receptor signaling. GAT211 was found to amplify the therapeutic effect of endocannabinoids without the negative side effects of psychoactivity or tolerance. GAT211 caused a CB1-dependent suppression of paclitaxel-induced mechanical and cold allodynia with no sign of tolerance over 19 days of administration. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |

