Nimorazole
SIGMA/SML1935 - ≥98% (HPLC)
Synonym: 4-
CAS Number: 6506-37-2
Empirical Formula (Hill Notation): C9H14N4O3
Molecular Weight: 226.23
EC Number: 229-394-4
Linear Formula: C9H14N4O3
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to beige |
| form | powder |
| InChI | 1S/C9H14N4O3/c14-13(15)9- |
| InChI key | MDJFHRLTPRPZLY-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | [N+](=O)([O-])c1[n](cnc1) |
| solubility | DMSO: 30 mg/mL, clear |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | A nitroimidazole-based hypoxic cell-radiation sensitizer and anti-infective against Trichomonas vaginalis. |
| Biochem/physiol Actions: | Nimorazole is a nitroimidazole-based hypoxic cell-radiation sensitizer with less toxicity than etanidazole or misonidazole. Under low oxygen (hypoxic) condition, reductive activation of its 5-nitroimidazole moiety leads to enhanced adduct formation with reduced glutathione, which form the basis of cancer/tumour-selective radiation sensitization. Nimorazole is also a known anti-infective agent against trichomoniasis, an infectious disease caused by the protozoan parasite Trichomonas vaginalis. |
| Symbol | GHS08 |
| Signal word | Danger |
| Hazard statements | H340 - H361d |
| Precautionary statements | P201 - P308 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |


