Synonym: 2-[4-(4-Nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester; 4-Thiazolidinecarboxylic acid, 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-, ethyl ester
CAS Number: 415697-08-4
Empirical Formula (Hill Notation): C20H22N2O5S
Molecular Weight: 402.46
MDL Number: MFCD06798326
Linear Formula: C20H22N2O5S
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C20H22N2O5S/c1-2-26-20(23)18-13-28-19(21-18)11-14-5-9-17(10-6-14)27-12-15-3-7-16(8-4-15)22(24)25/h3-10,18-19,21H,2,11-13H2,1H3 |
| InChI key |
ZVYIJXLMBWCGHP-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
O=C(OCC)C1CSC(CC2=CC=C(OCC3=CC=C([N+]([O-])=O)C=C3)C=C2)N1 |
| solubility |
DMSO: 2 mg/mL, clear |
| storage condition |
desiccated |
| storage temp. |
2-8°C |
| Application: |
SN-6 has been used as a selective Na+/Ca++ exchanger (NCX) inhibitor to study its neuroprotective effects on axonal injury in mice. |
| Biochem/physiol Actions: |
Selective Na+/Ca++ exchange (NCX) inhibitor |
| Biochem/physiol Actions: |
SN-6 is a selective inhibitor of Na+/Ca++ exchanger (NCX) with some selectivity for the NCX1 isoform. |
| Biochem/physiol Actions: |
SN-6 is involved in safeguarding against hypoxia and reoxygenation‐induced cell damage in renal tubular cells. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
