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ADDA 5 hydrochloride

SIGMA/SML1940 - ≥98% (HPLC)

Synonym: 1-[2-(1-Adamantyl)ethoxy]-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-propanol hydrochloride; 3,4-Dihydro-α-[(2-tricyclo[3.3.1.13,7]dec-1-ylethoxy)methyl]-2(1H)-isoquinolineethanol hydrochloride

CAS Number: 473268-46-1
Empirical Formula (Hill Notation): C24H35NO2 · HCl
Molecular Weight: 406.00
Linear Formula: C24H35NO2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1940-5MG 5 mg
 $116.00
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45-SML1940-25MG 25 mg
 $372.00
1/EA		 Add To Favorites
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This image depicts SML1940-5MG.

 

assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
SMILES string OC(CN1CCC(C=CC=C2)=C2C1)COCCC34C[C@H]5C[C@H](C[C@H](C5)C4)C3.[H]Cl
solubility DMSO: 2 mg/mL, clear
storage condition desiccated
storage temp. 2-8°C
Application: ADDA 5 hydrochloride has been used as a complex IV inhibitor to study its effects on leptomeningeal derivatives of human breast and lung cancer cells.
Biochem/physiol Actions: ADDA 5 is a potent and selective inhibitor of cytochrome c oxidase (Complex IV) that depletes the bioenergetics reserve capacity in intact glioma cells. ADDA 5 specifically inhibits the proliferation of chemosensitive and chemoresistant glioma cells, while sparing non-cancer cells. Additionally ADDA 5 is effective against glioma stem cells.
Biochem/physiol Actions: Potent and selective inhibitor of cytochrome c oxidase (Complex IV)
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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