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CGP3466B maleate salt

SIGMA/SML1941 - ≥98% (HPLC)

Synonym: CGP 3466B; Dibenz[b,f]oxepin-10-methanamine, N-methyl-N-2-propyn-1-yl-, (2Z)-2-butenedioate (1:1); N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-methyl-N-(2-propynyl)amine monomaleic acid salt; Omigapil maleate salt; TCH346

CAS Number: 200189-97-5
Empirical Formula (Hill Notation): C19H17NO · C4H4O4
Molecular Weight: 391.42
Linear Formula: C19H17NO · C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1941-5MG 5 mg
 $98.40
1/EA		 Add To Favorites
45-SML1941-25MG 25 mg
 $397.00
1/EA		 Add To Favorites
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C19H17NO.C4H4O4/c1-3-12-20(2)14-16-13-15-8-4-6-10-18(15)21-19-11-7-5-9-17(16)19;5-3(6)1-2-4(7)8/h1,4-11,13H,12,14H2,2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key SQAZQLMBEHYFJA-BTJKTKAUSA-N
Quality Level 100 
SMILES string N(CC1=Cc2c(cccc2)Oc3c1cccc3)(CC#C)C.OC(=O)C=C/C(=O)O
solubility DMSO: 2 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: CGP3466B, also known as Omigapil maleate and TCH346, is a potent inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH). It has been shown to have neuroprotective activity and received U.S. FDA Fast Track Designation for the treatment of congenital muscular dystrophy in May 2016.
Biochem/physiol Actions: Inhibitor of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), neuroprotective.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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