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IWP-O1

SIGMA/SML1962 - ≥98% (HPLC)

Synonym: IWP-O1; 5-Phenyl-N-(5-phenylpyridin-2-yl)-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-acetamide; IWP-01

CAS Number: 2074607-48-8
Empirical Formula (Hill Notation): C26H20N6O
Molecular Weight: 432.48
Linear Formula: C26H20N6O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1962-5MG 5 mg
 $190.00
1/EA		 Add To Favorites
This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color white to beige
form powder
InChI key GYYDQHBKIHQHEB-UHFFFAOYSA-N
Quality Level 100 
SMILES string [n]3(nnc(c3c5ccccc5)c4ccncc4)CC(=O)Nc1ncc(cc1)c2ccccc2
solubility DMSO: 25 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: IWP-O1 is an inhibitor of Porcupine (Porcn), an acyl (palmitoyl) transferase essential for secretion of Wnt proteins and involved in both embryonic development and tumor progression. IWP-O1 has good metabolic stability and is extremely potent, exhibiting an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling.
Biochem/physiol Actions: Porcn Inhibitor
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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