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PKUMDL-WQ-2101

SIGMA/SML1970 - ≥98% (HPLC)

Synonym: 2,4-Dihydroxy-benzoic acid 2-[(2-hydroxy-5-nitrophenyl)methylene]hydrazide

CAS Number: 304481-72-9
Empirical Formula (Hill Notation): C14H11N3O6
Molecular Weight: 317.25
Linear Formula: C14H11N3O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1970-5MG 5 mg
 $116.00
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45-SML1970-25MG 25 mg
 $467.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

assay ≥98% (HPLC)
color light yellow to dark orange
form powder
Quality Level 100 
solubility DMSO: 2 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: PKUMDL-WQ-2101 is a potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) that selectively inhibits serine synthesis in cancer cells. PKUMDL-WQ-2101 binds to allosteric site I, which is located close to active site. PKUMDL-WQ-2101 inhibits tumor growth of MDA-MB-468 xenografts in mice.
Biochem/physiol Actions: Potent and selective non-NAD+-competing allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH)
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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