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PS432

SIGMA/SML1991 - ≥98% (HPLC)

Synonym: 2-[5-(4-chlorophenyl)-2-furanyl]-2,5-dihydro-4-hydroxy-1-(6-methyl-2-benzothiazolyl)-5-oxo-1H-pyrrole-3-carboxylic acid ethyl ester

CAS Number: 2083630-26-4
Empirical Formula (Hill Notation): C25H19ClN2O5S
Molecular Weight: 494.95
Linear Formula: C25H19ClN2O5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML1991-5MG 5 mg
 $78.40
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
shipped in ambient
SMILES string O=C1C(O)=C(C(OCC)=O)C(C2=CC=C(C3=CC=C(Cl)C=C3)O2)N1C4=NC(C=CC(C)=C5)=C5S4
solubility DMSO: 2 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Allosteric inhibitor of atypical PKC isoforms
Biochem/physiol Actions: PS432 is an allosteric inhibitor of Protein Kinase C (PKC) that targets regulatory site (PIF-pocket) present in the kinase domain. PS432 potently inhibits non-small cell lung cancer cells proliferation and tumor growth without side effects in a mouse xenograft model.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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