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Lalistat 2

SIGMA/SML2053 - ≥98% (HPLC)

Synonym: 1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester; Lalistat-2

CAS Number: 1234569-09-5
Empirical Formula (Hill Notation): C13H20N4O2S
Molecular Weight: 296.39
MDL Number: MFCD31544494
Linear Formula: C13H20N4O2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML2053-5MG 5 mg
 No Price  
45-SML2053-25MG 25 mg
 $467.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI key PNYYVHOTXOEBEV-UHFFFAOYSA-N
Quality Level 200 
SMILES string O=C(N1CCCCC1)OC2=NSN=C2N3CCCCC3
solubility DMSO: 2 mg/mL, clear
storage temp. 2-8°C
Application: Lalistat 2 has been used as a lysosomal acid lipase (LAL) inhibitor to study its effects on hypoxia-inducible factor (HIF) in mice. It has also been used as a LAL inhibitor to study LAL activity on dried blood spot cards.
Biochem/physiol Actions: Lalistat-2 is a potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa). Lalistat-2 affects lipid droplets morphology and localization.
Biochem/physiol Actions: potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa).
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 41106300

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