Davunetide trifluoroacetate salt
SIGMA/SML2063 - ≥95% (HPLC)
Synonym: AL-108; Asn-
CAS Number: 211439-12-2 (free base)
Empirical Formula (Hill Notation): C36H60N10O12 · xC2HF3O2
Molecular Weight: 824.92 (free base basis)
Linear Formula: C36H60N10O12 · xC2HF3O2
Product Type: Chemical
| assay | ≥95% (HPLC) |
| color | white to beige |
| composition | Peptide content, ≥60% |
| form | powder |
| InChI | 1S/C36H60N10O12/c1-6-18(4 |
| InChI key | DWLTUUXCVGVRAV-XWRHUKJGSA |
| shipped in | wet ice |
| SMILES string | N2([C@@H](CCC2)C(=O)N[C@@ |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Davunetide (NAPVSIPQ; NAP) is an eight amino acid peptide identified as the active component of activity-dependent neuroprotective protein (ADNP). It has been found to be neuro-protective at femtomolar concentrations in vitro against the neural toxicity of a wide range of compounds. Davunetide has been investigated for Parkinson′s disease and schizophrenia and in clinical trials for Alzheimner′s Disease, targeting microtubule-tau Interaction. |
| Biochem/physiol Actions: | Neuroprotective peptide; the neuronal tubulin-preferring agent |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |
