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ST034307

SIGMA/SML2109 - ≥98% (HPLC)

Synonym: 6-Chloro-2-(trichloromethyl)-4H-1-benzopyran-4-one; 6-Chloro-2-(trichloromethyl)chromen-4-one

CAS Number: 133406-29-8
Empirical Formula (Hill Notation): C10H4Cl4O2
Molecular Weight: 297.95
MDL Number: MFCD00760793
Linear Formula: C10H4Cl4O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML2109-5MG 5 mg
 $91.60
1/EA		 Add To Favorites
45-SML2109-25MG 25 mg
 $371.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color faint green to dark gray
form powder
SMILES string ClC(Cl)(Cl)C1=CC(C2=CC(Cl)=CC=C2O1)=O
solubility DMSO: 2 mg/mL, clear (warmed)
storage temp. −20°C
Biochem/physiol Actions: ST034307 is a selective inhibitor of adenylyl cyclase 1 (AC1) with analgesic activity. Adenylyl cyclase 1 has been shown to be a potential target for treating pain and reducing the dependency on opioids, but it has been difficult to inhibit AC1 selectively without also inhibiting other isoforms vital to physiological functions. ST034307 is selective for AC1 over all eight other adenylyl cyclase isoforms. It inhibited AC1 and reduced cAMP, while leaving AC8 unaffected and was shown to reduce pain in a mouse inflammatory pain model.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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